Intended Honors Thesis: Neurolenin as a Potential Drug Candidate for Lymphatic Filariasis
I am currently researching Neurolenin as a drug development candidate to fight Lymphatic Filariasis (Lf), a neglected tropical disease.
I am working with the Shea Lab to synthesize different sesquiterpene lactones from a plant, Neurolena Labota (found in Central and South America) that has shown biological anti-parasitic properties against Lf, using Brugia pahangi our parasitic nematode animal model. We are trying to find the most appropriate concentrations of the compound that contribute to 100% death at a certain time and move forward with animal testing, with a potential partnership with Glaxo Smith Klein.
“Identification of Centella asiatica, Neurolaena lobota, and Quisqualis indica as medicinal herbs containing antifilarial activity to target lymphatic filariasis parasites.“Journal of the Smith College Women in Science 2014, SURF Abstract, 2014.
I have a twin sister who is studying Environmental Engineering at UCLA