Bruker LSFM

Instrument name: Bruker Luxendo MuVi-SPIM Light Sheet fluorescence Microscope (LSFM)

The LSFM is used to study large optically cleared or live fluorescently labelled samples. Two Laser sheets pass through the sample illuminating only a thin (2 – 8 um) slice of the sample. Fluorescent signal is detected perpendicular to the sheet of light passing through the sample and provides the researcher with a stack of close-to-confocal-resolution images. The system is equipped with environmental controls for temperature, 02, CO2 and humidity.  This is a fast, 3D bio-imaging techniques allowing researchers to examine various sample types over longer periods of time.  Limited training is available.

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