Second Messengers in Arthropod Photoreceptor Cells

 

Source: Hardie, R. C. and Raghu, P. (2001) Visual transduction in Drosophila. Nature 413: 186-193.

The diagram shows the major elements that link the capture of a photon of light to the opening of membrane channels.

Rhodopsin is the visual pigment molecule. Each molecule can capture one photon of light, which activates it.

G is the G-protein activated by rhodopsin. The G-protein activates phospholipase C (PLC), which opens the channels through a series of intermediate steps.

TRP is the transient receptor protein channel. When open, it allows Ca++ and other small cations to enter, depolarizing the photoreceptor cell.

 

View a diagram of the phototransduction cascade.