Elizabeth Jamieson

Associate Professor of Chemistry
Smith College

Office: Ford Hall 205A
Phone: (413)-585-7588
Fax: (413)-585-3786
Email: ejamieso(at)smith.edu

EDUCATION

Ph.D., Massachusetts Institute of Technology, Inorganic Chemistry
Advisor, Steve Lippard

B.A., Smith College, Chemistry

PROFESSIONAL HISTORY

Smith College, 2001-present
Assistant Professor of Chemistry

Boston University
Postdoctoral Fellow, 2000-2001
Advisor, Tom Tullius

COURSES

CHM 111: Introduction to Chemistry I
CHM 118: Advanced General Chemistry
CHM 224: General Chemistry, IV
CHM 363: Advanced Inorganic Chemistry
CHM 369: Bioinorganic Chemistry
BCH 252: Biochemistry I
BCH 352: Biochemistry II

RESEARCH INTERESTS

Bioinorganic chemistry. My lab is interested in examining how complexes of the transition metal chromium damage DNA. We use differential scanning calorimetry to see how lesions formed by chromium alter the thermodynamic stability of the DNA helix. We are also interested in investigating the structure of some of these lesions using NMR spectroscopy and in seeing how they affect the structure of nucleosomes. 

SELECTED PUBLICATIONS

Jamieson, E.R., Eppley, H.J., Geselbracht, M.J., Johnson, A.R., Reisner, B.A., Smith, S.R., Stewart, J.L., Watson, L.A., and Williams, B.S. “Inorganic Chemistry and IONiC: An Online Community Bringing Cutting Edge Research into the Classroom,” Inorg. Chem. 2011, 50, 5849-5854.

Stansfield, H.E., Kulczewski, B.P., Lybrand, K.E., Jamieson, E.R., "Identifying Protein Interactions with Metal-Modified DNA Using Microarray Technology," J. Biol. Inorg. Chem., 2009, 14, 193-199.

Chinyengetere, F., Jamieson, E.R., "Impact of the Oxidized Guanine Lesion Spiroiminodihydantoin on the Conformation and Thermodynamic Stability of a 15-mer DNA Duplex," Biochemistry, 2008, 47, 2584-2591. 

Chowdhury, T., Jamieson, E.R., "C4' Sugar Oxidation of Deoxyribonucleotide Triphosphates by Chromium(V) Complexes," Mutation Research, 2006, 610, 66-73. 

Chen, B., Jamieson, E.R., Tullius, T.D., "A General Synthesis of Specifically Deuterated Nucleotides for Studies of DNA and RNA," Bioorganic and Medicinal Chemistry Letters 2002, 12, 3093-3096.

Jamieson, E.R., Lippard, S.J., "Stopped-Flow Fluorescence Studies of HMG-Domain Protein Binding to Cisplatin-Modified DNA" Biochemistry, 2000, 39, 8426-8438.

Jamieson, E.R., Lippard, S.J., "Structure, Recognition, and Processing of Cisplatin-DNA Adducts," Chem. Rev. 1999, 99, 2467-2498.