Tanya Schneider

Ph.D., Yale University, Organic Chemistry, 2001
Thesis: "Protein-Mediated Regulation of Dimeric Transcription Factor Assembly and Protein Kinase Activity"
Advisor: Alanna Schepartz

B.A., Williams College, Chemistry, 1994
Thesis: "The Bioactivity of Southeast Asian Dart Poison Components"
Advisor: David P. Richardson

Smith College, 2008- 
Visiting Assistant Professor of Chemistry

EnviroLogix, 2004-2008
Senior Scientist

Harvard Medical School, 2001-2004
American Cancer Society Postdoctoral Fellow
Advisor: Christopher T. Walsh

Fall 2008: CHM 223: Chemistry III: Organic Chemistry
Spring 2009: CHM 222: Chemistry II: Organic Chemistry

Biosynthesis of natural products-how do enzymes catalyze the production of important bioactive molecules, and how can we reengineer this process to arrive at new derivatives with enhanced properties? We are currently focused on antibiotic biosynthesis and new routes to mitigate the problem of antibiotic resistance.  

T. L. Schneider & B. R. Linton, "Introduction to protein structure through genetic diseases," J. Chem. Ed. 2008, 85, 662-665.

T. L. Schneider, R. S. Mathew, K. P. Rice, K. Tamaki, J. L. Wood & A. Schepartz, "Increasing the kinase specificity of K252a by protein surface recognition," Org. Lett. 2005, 7, 1695-1698.

T. L. Schneider & C. T. Walsh, "Portability of oxidase domains in nonribosomal peptide synthetase modules," Biochemistry 2004, 43, 15946-15955.  

T. L. Schneider, B. Shen & C. T. Walsh, "Oxidase domains in epothilone and bleomycin biosynthesis: thiazoline to thiazole oxidation during chain elongation," Biochemistry 2003, 42, 9722-9730.  

T. L. Schneider, C. T. Walsh & S. E. O'Connor, "Utilization of alternate substrates by the first three modules of the epothilone synthetase assembly line," J. Am. Chem. Soc. 2002, 124, 11272-11273.  

T. L. Schneider & A. Schepartz, "Hepatitis B virus protein pX enhances monomer assembly pathway of bZIP^.DNA complexes," Biochemistry 2001, 40, 2835-2843.  

C. A. Carter, R. W. Forney, E. A. Gray, A. M. Gehring, T. L. Schneider, D. B. Young, C. M. Lovett, Jr., L. Scott, A. C. Messer & D. P. Richardson, "Toxicarioside A. A new cardenolide isolated from Antiaris toxicaria latex-derived dart poison. Assignment of the ¹H- and ¹³C-NMR shifts for an antiarigenin aglycone," Tetrahedron 1997, 53, 13557-13566.