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Assistant Professor of Chemistry
Smith College
Office: Sabin Reed 318
Phone: (413)-585-7588
Fax: (413)-585-3786
Email: ejamieso(at)email.smith.edu
Ph.D., Massachusetts Institute of Technology, Inorganic Chemistry
Advisor, Steve Lippard
B.A., Smith College, Chemistry
Smith College, 2001-present
Assistant Professor of Chemistry
Boston University
Postdoctoral Fellow, 2000-2001
Advisor, Tom Tullius
CHM 111: Introduction to Chemistry I
CHM 118: Advanced General Chemistry
CHM 224: General Chemistry, IV
CHM 363: Advanced Inorganic Chemistry
CHM 369: Bioinorganic Chemistry
BCH 252: Biochemistry I
BCH 352: Biochemistry II
Bioinorganic chemistry. My lab is interested in examining various types of DNA damage caused by the transition metal, chromium, in order to understand how this metal causes cancer. We use uv spectroscopic methods and differential scanning calorimetry to examine changes to DNA stability caused by chromium-induced DNA damage. In addition, we are exploring the use of protein microarrays to search for cellular proteins that interact with these lesions.
Stansfield, H.E., Kulczewski, B.P., Lybrand, K.E., Jamieson, E.R., "Identifying Protein Interactions with Metal-Modified DNA Using Microarray Technology," Submitted.
Chinyengetere, F., Jamieson, E.R., "Impact of the Oxidized Guanine Lesion Spiroiminodihydantoin on the Conformation and Thermodynamic Stability of a 15-mer DNA Duplex," Biochemistry, 2008, 47, 2584-2591.
Chowdhury, T., Jamieson, E.R., "C4' Sugar Oxidation of Deoxyribonucleotide Triphosphates by Chromium(V) Complexes," Mutation Research, 2006, 610, 66-73.
Chen, B., Jamieson, E.R., Tullius, T.D., "A General Synthesis of Specifically Deuterated Nucleotides for Studies of DNA and RNA," Bioorganic and Medicinal Chemistry Letters 2002, 12, 3093-3096.
Jamieson, E.R., Lippard, S.J., "Stopped-Flow Fluorescence Studies of HMG-Domain Protein Binding to Cisplatin-Modified DNA" Biochemistry, 2000, 39, 8426-8438.
Jamieson, E.R., Lippard, S.J., "Structure, Recognition, and Processing of Cisplatin-DNA Adducts," Chem. Rev. 1999, 99, 2467-2498.
