CHM 357 - TOPICS IN BIOCHEMISTRY:

PHARMACOLOGY

Last Modified 14 April 2008

Course Description

Selected Topics in Biochemistry: Pharmacology and Drug Design. An introduction to pharmacology, toxicology and drug design. The design and pharmacology of several drugs will be examined in detail, and the computational software used to design a drug and model the drug and its binding site. The ethical and legal considerations of drug design, manufacture and use will also be considered. Prerequisite: BCH 252b, or permission of the instructor. Offered in altenate years; next offered in spring, 2009. {N} 3 credits. David Bickar

Chemistry 357a materials available:

Pharmacological Links:

ACSWeb - American Chemical Society Resources
Blast - Search for or compare sequences of proteins or DNA for similarity
Drug Metabolism and Disposition - Pharmacology - free abstracts only.
Enzyme - Database of enzymes, searchable by name, number, function, cofactors, ...
Enzymatic Pathways - Find enzymatic pathways by enzymes or metabolites
ExPASy - home page of one of the largest protein and nucleic acid sequence databases and a great collection of tools for protein/DNA/RNA sequence and structure analysis and visualization. Includes SwissModel and Swiss-PdbViewer and a large collection of useful links.
Entrez Query - Search the combined NCBI databases
Molecular Pharmacology - Journal with often excellent articles
National Center for Biotechnology Information (NCBI) - Homepage for Blast, Entrez and PubMed.
PDB browser - (Protein Database- Database of all known protein/DNA/RNA molecular structures
PubMed - Search engine for Medline literature database
Pharmacological Reviews - some available
Pharmacology and Experimental Therapeutics - Good journal, and free!

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